Kinase profiling results of kinases in KIF 2ACXA_ANP (GRK6, PDB code: 2ACX, chain A)
Template Kinase: GRK6
Template inhibitor: Phosphoaminophosphonic Acid-Adenylate Ester

 23 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
AKT2AGC
ROCK1AGC
PDPK1AGC
PRKCIAGC
STK11CAMK
CASKCAMK
DAPK1CAMK
MAPKAPK23
CHEK2CAMK
CDK2CMGC
CSNK2A1CMGC
GSK3BCMGC
MAPK10CMGC
MAPK12CMGC
AURKAOther
NEK7Other
PLK1Other
TTKOther
OXSR1STE
STK24STE
MAP2K1STE

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
AKT2AGC
GRK6AGC
PDPK1AGC
PRKCIAGC
ROCK1AGC
SGK1AGC
CHEK2CAMK
DAPK1CAMK
MAPKAPK2CAMK
STK11CAMK
CDK2CMGC
CSNK2A1CMGC
GSK3BCMGC
MAPK10CMGC
MAPK12CMGC
AURKAOther
NEK7Other
PLK1Other
TTKOther
MAP2K1STE
OXSR1STE
STK24STE