Kinase profiling results of kinases in KIF 1R0EA_DFN (GSK3B, PDB code: 1R0E, chain A)
Template Kinase: GSK3B
Template inhibitor: HMS3401D14

 17 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
CDK2CMGC 
CDK3CMGC 
CDK5CMGC 
CDK9CMGC 
PCTK1CMGC 
PCTK2CMGC 
PCTK3CMGC 
CLK1CMGC 
CLK2CMGC 
CLK3CMGC 
CLK4CMGC 
DYRK1BCMGC 
GSK3ACMGC 
GSK3BCMGC 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
PRKCAAGC 
CDC2CMGC 
CDC2CMGC 
CDK2CMGC 
CDK3CMGC 
CDK5CMGC 
CDK6CMGC 
CDK6CMGC 
CDK9CMGC 
CLK1CMGC 
CLK2CMGC 
CLK3CMGC 
CLK4CMGC 
DYRK1BCMGC 
GSK3ACMGC 
GSK3BCMGC