Kinase profiling results of kinases in KIF 2C0OA_L2G (HCK, PDB code: 2C0O, chain A)
Template Kinase: HCK
Template inhibitor: A-770041

41 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C C
RPS6KA1AGC    
RPS6KA1CAMK    
RPS6KA2AGC    
RPS6KA2CAMK    
RPS6KA6AGC    
RPS6KA6CAMK    
CHEK1CAMK    
DAPK1CAMK    
DAPK3CAMK    
CDK2CMGC    
MAPK14CMGC    
NEK3Other    
NEK2Other    
PLK1Other    
PLK2Other    
PLK3Other    
STK10STE    
ABL1TK    
TNK1TK    
TNK2TK    
ALKTK    
LTKTK    
CSKTK    
EGFRTK    
ERBB2TK    
PTK2TK    
PTK2BTK    
FESTK    
IGF1RTK    
INSRTK    
JAK2TK    
JAK3TK    
CSF1RTK    
KITTK    
FYNTK    
SRCTK    
HCKTK    
LCKTK    
LYNTK    
SYKTK    
ITKTK    
IRAK1TKL    
IRAK4TKL    
RAF1TKL    

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C
RPS6KA1AGC    
RPS6KA2AGC    
RPS6KA6AGC    
CHEK1CAMK    
DAPK1CAMK    
DAPK3CAMK    
CDK2CMGC    
MAPK14CMGC    
NEK2Other    
NEK3Other    
PLK1Other    
PLK2Other    
PLK3Other    
STK10STE    
ABL1TK    
ALKTK    
CSF1RTK    
CSKTK    
EGFRTK    
ERBB2TK    
FESTK    
FYNTK    
HCKTK    
IGF1RTK    
INSRTK    
ITKTK    
JAK2TK    
JAK3TK    
KITTK    
LCKTK    
LTKTK    
LYNTK    
PTK2TK    
PTK2BTK    
SRCTK    
SYKTK    
TNK2TK    
IRAK1TKL    
IRAK4TKL    
RAF1TKL