Kinase profiling results of kinases in KIF 3I81A_EBI (IGF1R, PDB code: 3I81, chain A)
Template Kinase: IGF1R
Template inhibitor: BMS-754807

4 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C C
IGF1RTK    
JAK2TK    
TEKTK    
NTRK1TK    

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C
IGF1RTK   
JAK2TK   
NTRK1TK   
TEKTK