Kinase profiling results of kinases in KIF 3LVPA_PDR (IGF1R, PDB code: 3LVP, chain A)
Template Kinase: IGF1R
Template inhibitor: DNC009399

18 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
ABL1TK 
EGFRTK 
ERBB4TK 
EPHA6TK 
EPHB2TK 
EPHB4TK 
FGFR1TK 
IGF1RTK 
INSRTK 
RETTK 
SRCTK 
YES1TK 
LCKTK 
ITKTK 
TEKTK 
FLT4TK 
KDRTK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C
CDC2CMGC    
CDC2CMGC    
ABL1TK    
EGFRTK    
EPHA6TK    
EPHB2TK    
EPHB4TK    
ERBB4TK    
FGFR1TK    
FLT4TK    
IGF1RTK    
INSRTK    
ITKTK    
KDRTK    
LCKTK    
RETTK    
SRCTK    
TEKTK    
YES1TK