Kinase profiling results of kinases in KIF 3MJ2A_MJG (ITK, PDB code: 3MJ2, chain A)
Template Kinase: ITK
Template inhibitor: BMS-509744

6 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C
INSRTK  
FYNTK  
LCKTK  
BTKTK  
ITKTK  
NTRK1TK  

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
BTKTK 
FYNTK 
INSRTK 
ITKTK 
LCKTK 
NTRK1TK