Kinase profiling results of kinases in KIF 2RL5A_2RL (KDR, PDB code: 2RL5, chain A)
Template Kinase: KDR
Template inhibitor: Sorafenib

12 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C
ABL1TK  
DDR1TK  
FGFR1TK  
FGFR2TK  
METTK  
CSF1RTK  
KITTK  
PDGFRATK  
PDGFRBTK  
LCKTK  
FLT4TK  
KDRTK  

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C
ABL1TK  
CSF1RTK  
FGFR1TK  
FGFR2TK  
FLT4TK  
KDRTK  
KITTK  
LCKTK  
METTK  
PDGFRATK  
PDGFRBTK