Kinase profiling results of kinases in KIF 3C7QA_XIN (KDR, PDB code: 3C7Q, chain A)
Template Kinase: KDR
Template inhibitor: BIBF1120

25 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
ABL1TK 
ABL2TK 
DDR1TK 
EPHA1TK 
EPHA3TK 
PTK2BTK 
FGFR1TK 
INSRTK 
METTK 
MUSKTK 
KITTK 
PDGFRATK 
PDGFRBTK 
LCKTK 
BTKTK 
ITKTK 
TXKTK 
TEKTK 
TIE1TK 
NTRK2TK 
NTRK3TK 
FLT1TK 
FLT4TK 
KDRTK 
RIPK1TKL 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
ABL1TK
ABL2TK
BTKTK
EPHA1TK
EPHA3TK
FGFR1TK
FLT1TK
FLT4TK
INSRTK
ITKTK
KDRTK
KITTK
LCKTK
METTK
MUSKTK
NTRK2TK
NTRK3TK
PDGFRATK
PDGFRBTK
PTK2BTK
TEKTK
TXKTK