Kinase profiling results of kinases in KIF 3EFLA_706 (KDR, PDB code: 3EFL, chain A)
Template Kinase: KDR
Template inhibitor: Motesanib

15 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C C C C
ABL1TK      
ABL2TK      
DDR1TK      
FGFR1TK      
INSRTK      
KITTK      
PDGFRATK      
PDGFRBTK      
LCKTK      
ITKTK      
TEKTK      
FLT1TK      
FLT4TK      
KDRTK      
BRAFTKL      

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C C
ABL1TK      
ABL2TK      
FGFR1TK      
FLT1TK      
FLT4TK      
INSRTK      
ITKTK      
KDRTK      
KITTK      
LCKTK      
PDGFRATK      
PDGFRBTK      
TEKTK      
BRAFTKL