Kinase profiling results of kinases in KIF 2OF2A_547 (LCK, PDB code: 2OF2, chain A)
Template Kinase: LCK
Template inhibitor: DB07146

 7 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
CDK2CMGC
AURKAOther
TNK2TK
FGFR1TK
PDGFRBTK
LCKTK
ITKTK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
CDK2CMGC 
AURKAOther 
FGFR1TK 
ITKTK 
LCKTK 
PDGFRBTK 
TNK2TK