Kinase profiling results of kinases in KIF 2ZM1A_KSF (LCK, PDB code: 2ZM1, chain A)
Template Kinase: LCK
Template inhibitor: DB08055

17 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
CDK2CMGC 
MAPK14CMGC 
AURKAOther 
EIF2AK2Other 
ABL1TK 
ALKTK 
EGFRTK 
EPHA6TK 
FGFR1TK 
IGF1RTK 
JAK2TK 
SRCTK 
LCKTK 
IRAK4TKL 
TGFBR1TKL 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C
PRKCAAGC    
CDC2CMGC    
CDC2CMGC    
CDK2CMGC    
MAPK14CMGC    
AURKAOther    
ABL1TK    
ALKTK    
EGFRTK    
EPHA6TK    
FGFR1TK    
IGF1RTK    
JAK2TK    
LCKTK    
SRCTK    
IRAK4TKL    
TGFBR1TKL