Kinase profiling results of kinases in KIF 3AC4A_KZL (LCK, PDB code: 3AC4, chain A)
Template Kinase: LCK
Template inhibitor: imidazo[1,2-c]pyrimidine-8-carboxamide, 10c

7 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
MAPK14CMGC 
CSF1RTK 
LCKTK 
SYKTK 
ZAP70TK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C
PRKCBAGC   
PRKCBAGC   
CDC2CMGC   
CDC2CMGC   
MAPK14CMGC   
CSF1RTK   
LCKTK   
SYKTK   
ZAP70TK