Kinase profiling results of kinases in KIF 3AD6A_KSC (LCK, PDB code: 3AD6, chain A)
Template Kinase: LCK
Template inhibitor: Erlotinib

13 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C
CDK2CMGC   
MAPK14CMGC   
AURKAOther   
INSRTK   
JAK2TK   
CSF1RTK   
SRCTK   
LCKTK   
SYKTK   
ZAP70TK   
ITKTK   

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C
PRKCBAGC  
PRKCBAGC  
CDC2CMGC  
CDC2CMGC  
CDK2CMGC  
MAPK14CMGC  
AURKAOther  
CSF1RTK  
INSRTK  
ITKTK  
JAK2TK  
LCKTK  
SRCTK  
SYKTK  
ZAP70TK