Kinase profiling results of kinases in KIF 3BYOA_AM9 (LCK, PDB code: 3BYO, chain A)
Template Kinase: LCK
Template inhibitor: AC1NS8OV

 28 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C
SIK1CAMK  
CDK2CMGC  
CDK5CMGC  
MAPK14CMGC  
AURKAOther  
AURKCOther  
EIF2AK2Other  
ABL1TK  
ALKTK  
EGFRTK  
FGFR1TK  
FGFR3TK  
IGF1RTK  
INSRTK  
JAK2TK  
CSF1RTK  
KITTK  
PDGFRATK  
PDGFRBTK  
RETTK  
SRCTK  
HCKTK  
LCKTK  
LYNTK  
NTRK1TK  
BRAFTKL  
TGFBR1TKL  

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C
CDC2CMGC    
CDC2CMGC    
CDK2CMGC    
CDK5CMGC    
MAPK14CMGC    
AURKAOther    
AURKCOther    
ABL1TK    
ALKTK    
CSF1RTK    
EGFRTK    
FGFR1TK    
FGFR3TK    
HCKTK    
IGF1RTK    
INSRTK    
JAK2TK    
KITTK    
LCKTK    
LYNTK    
NTRK1TK    
PDGFRATK    
PDGFRBTK    
RETTK    
SRCTK    
BRAFTKL    
TGFBR1TKL