Kinase profiling results of kinases in KIF 3MPMA_5LK (LCK, PDB code: 3MPM, chain A)
Template Kinase: LCK
Template inhibitor: GW_2580

4 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
CDK2CMGC
SRCTK
HCKTK
LCKTK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
CDK2CMGC
HCKTK
LCKTK
SRCTK