Kinase profiling results of kinases in KIF 1PMEA_SB2 (MAPK1, PDB code: 1PME, chain A)
Template Kinase: MAPK1
Template inhibitor: SB 203580

16 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
RPS6KA1AGC 
RPS6KA1CAMK 
RPS6KA6AGC 
RPS6KA6CAMK 
STK32AAGC 
GSK3BCMGC 
MAPK1CMGC 
MAPK10CMGC 
MAPK8CMGC 
NLKCMGC 
MAPK11CMGC 
MAPK12CMGC 
MAPK14CMGC 
EPHB2TK 
SRCTK 
LCKTK 
PTK6TK 
TXKTK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C
RPS6KA1AGC  
RPS6KA6AGC  
GSK3BCMGC  
MAPK1CMGC  
MAPK10CMGC  
MAPK11CMGC  
MAPK12CMGC  
MAPK14CMGC  
MAPK8CMGC  
NLKCMGC  
EPHB2TK  
LCKTK  
PTK6TK  
SRCTK  
TXKTK