Kinase profiling results of kinases in KIF 1WZYA_F29 (MAPK1, PDB code: 1WZY, chain A)
Template Kinase: MAPK1
Template inhibitor: AC1O4W7N

 27 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
PDPK1AGC 
CHEK1CAMK 
PRKD1CAMK 
PRKD2CAMK 
PRKD3CAMK 
CHEK2CAMK 
CDK2CMGC 
CDK4CMGC 
GSK3BCMGC 
MAPK1CMGC 
MAPK8CMGC 
MAPK14CMGC 
CSKTK 
EPHA1TK 
EPHA4TK 
EPHA5TK 
EPHB1TK 
EPHB2TK 
EPHB3TK 
EPHB4TK 
FYNTK 
SRCTK 
YES1TK 
HCKTK 
LCKTK 
PTK6TK 
TXKTK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C
PDPK1AGC   
CHEK1CAMK   
CHEK2CAMK   
PRKD1CAMK   
PRKD2CAMK   
PRKD3CAMK   
CDK2CMGC   
CDK4CMGC   
GSK3BCMGC   
MAPK1CMGC   
MAPK14CMGC   
MAPK8CMGC   
CSKTK   
EPHA1TK   
EPHA4TK   
EPHA5TK   
EPHB1TK   
EPHB2TK   
EPHB3TK   
EPHB4TK   
FYNTK   
HCKTK   
LCKTK   
PTK6TK   
SRCTK   
TXKTK   
YES1TK