Kinase profiling results of kinases in KIF 2OJGA_19A (MAPK1, PDB code: 2OJG, chain A)
Template Kinase: MAPK1
Template inhibitor: Oprea1_828620

 8 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
CHEK1CAMK
CHEK2CAMK
CDK2CMGC
CDK4CMGC
GSK3ACMGC
GSK3BCMGC
MAPK1CMGC
LCKTK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
CHEK1CAMK 
CHEK2CAMK 
CDK2CMGC 
CDK4CMGC 
GSK3ACMGC 
GSK3BCMGC 
MAPK1CMGC 
LCKTK