Kinase profiling results of kinases in KIF 1JNKA_ANP (MAPK10, PDB code: 1JNK, chain A)
Template Kinase: MAPK10
Template inhibitor: Phosphoaminophosphonic Acid-Adenylate Ester

 15 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
PDPK1AGC
CASKCAMK
DAPK1CAMK
CHEK2CAMK
CDK2CMGC
CDK9CMGC
CSNK2A1CMGC
GSK3BCMGC
MAPK10CMGC
MAPK12CMGC
AURKAOther
NEK2Other
STK24STE

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
GRK6AGC
PDPK1AGC
CHEK2CAMK
DAPK1CAMK
PASKCAMK
CDK2CMGC
CDK9CMGC
CSNK2A1CMGC
GSK3BCMGC
MAPK10CMGC
MAPK12CMGC
AURKAOther
NEK2Other
STK24STE