Kinase profiling results of kinases in KIF 1PMVA_537 (MAPK10, PDB code: 1PMV, chain A)
Template Kinase: MAPK10
Template inhibitor: 1,9-Pyrazoloanthrone

10 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
PRKD1CAMK
PRKD2CAMK
PRKD3CAMK
CHEK2CAMK
CDK2CMGC
CDK5CMGC
MAPK10CMGC
MAPK8CMGC
MAPK9CMGC
MAPK12CMGC

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C C
CHEK2CAMK      
PRKD1CAMK      
PRKD2CAMK      
PRKD3CAMK      
CDK2CMGC      
CDK5CMGC      
MAPK10CMGC      
MAPK12CMGC      
MAPK8CMGC      
MAPK9CMGC