Kinase profiling results of kinases in KIF 2O2UA_738 (MAPK10, PDB code: 2O2U, chain A)
Template Kinase: MAPK10
Template inhibitor: 2-[(2-chlorobenzoyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide

9 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
CHEK1CAMK
CHEK2CAMK
MAPK10CMGC
MAPK8CMGC
MAPK9CMGC
MAPK14CMGC
AURKAOther
AURKBOther
AURKCOther

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C
CHEK1CAMK  
CHEK2CAMK  
MAPK10CMGC  
MAPK14CMGC  
MAPK8CMGC  
MAPK9CMGC  
AURKAOther  
AURKBOther  
AURKCOther