Kinase profiling results of kinases in KIF 3OY1A_589 (MAPK10, PDB code: 3OY1, chain A)
Template Kinase: MAPK10
Template inhibitor: 5-[2-(Cyclohexylamino)pyridin-4-Yl]-4-Naphthalen-2-Yl-2-(Tetrahydro-2h-Pyran-4-Yl)-2,4-Dihydro-3h-1,2,4-Triazol-3-One

 4 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
MAPK10CMGC
MAPK8CMGC
MAPK9CMGC
MAPK14CMGC

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
MAPK10CMGC
MAPK14CMGC
MAPK8CMGC
MAPK9CMGC