Kinase profiling results of kinases in KIF 3GC9A_B45 (MAPK11, PDB code: 3GC9, chain A)
Template Kinase: MAPK11
Template inhibitor: Sunitinib

 4 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
MAPK8CMGC 
MAPK11CMGC 
MAPK14CMGC 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C
CDC2CMGC  
CDC2CMGC  
MAPK11CMGC  
MAPK14CMGC  
MAPK8CMGC