Kinase profiling results of kinases in KIF 1CM8A_ANP (MAPK12, PDB code: 1CM8, chain A)
Template Kinase: MAPK12
Template inhibitor: Phosphoaminophosphonic Acid-Adenylate Ester

 16 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
AKT2AGC
PDPK1AGC
DAPK1CAMK
CHEK2CAMK
CDK2CMGC
CDK9CMGC
CSNK2A1CMGC
GSK3BCMGC
MAPK10CMGC
MAPK12CMGC
AURKAOther
PLK1Other
TTKOther
STK24STE
SRCTK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
AKT2AGC
GRK6AGC
PDPK1AGC
CHEK2CAMK
DAPK1CAMK
CDK2CMGC
CDK9CMGC
CSNK2A1CMGC
GSK3BCMGC
MAPK10CMGC
MAPK12CMGC
AURKAOther
PLK1Other
TTKOther
STK24STE
SRCTK