Kinase profiling results of kinases in KIF 1W84A_L12 (MAPK14, PDB code: 1W84, chain A)
Template Kinase: MAPK14
Template inhibitor: 3-(2-Pyridin-4-yl-ethyl)-1H-indole

6 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
PRKACAAGC
CDK2CMGC
CDK5CMGC
GSK3BCMGC
MAPK14CMGC
LCKTK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C
PRKACAAGC   
CDK2CMGC   
CDK5CMGC   
GSK3BCMGC   
MAPK14CMGC   
LCKTK