Kinase profiling results of kinases in KIF 1YQJA_6NP (MAPK14, PDB code: 1YQJ, chain A)
Template Kinase: MAPK14
Template inhibitor: AMG_706

 19 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
PRKACAAGC
CHEK1CAMK
CHEK2CAMK
CDK2CMGC
CSNK2A1CMGC
GSK3BCMGC
MAPK10CMGC
MAPK8CMGC
MAPK9CMGC
MAPK11CMGC
MAPK14CMGC
CHUKOther
PLK1Other
ABL1TK
FGFR1TK
SRCTK
LCKTK
PTK6TK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
PRKACAAGC 
CHEK1CAMK 
CHEK2CAMK 
CDC2CMGC 
CDC2CMGC 
CDK2CMGC 
CSNK2A1CMGC 
GSK3BCMGC 
MAPK10CMGC 
MAPK11CMGC 
MAPK14CMGC 
MAPK8CMGC 
MAPK9CMGC 
CHUKOther 
PLK1Other 
ABL1TK 
FGFR1TK 
LCKTK 
PTK6TK 
SRCTK