Kinase profiling results of kinases in KIF 2BAKA_AQZ (MAPK14, PDB code: 2BAK, chain A)
Template Kinase: MAPK14
Template inhibitor: 2bak

8 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C C C C C C C C C C C C
MAPK9CMGC              
MAPK11CMGC              
MAPK14CMGC              
ABL1TK              
ABL2TK              
SRCTK              
YES1TK              
LCKTK              

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C
MAPK11CMGC     
MAPK14CMGC     
MAPK9CMGC     
ABL1TK     
ABL2TK     
LCKTK     
SRCTK     
YES1TK