Kinase profiling results of kinases in KIF 3DS6A_A17 (MAPK14, PDB code: 3DS6, chain A)
Template Kinase: MAPK14
Template inhibitor: 3ds6

 21 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C C C C
CHEK1CAMK      
PRKD1CAMK      
CHEK2CAMK      
CDK2CMGC      
CDK5CMGC      
CSNK2A1CMGC      
GSK3ACMGC      
GSK3BCMGC      
MAPK1CMGC      
MAPK10CMGC      
MAPK8CMGC      
MAPK9CMGC      
MAPK11CMGC      
MAPK12CMGC      
MAPK13CMGC      
MAPK14CMGC      
CHUKOther      
ABL1TK      
SRCTK      
LCKTK      

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C
CHEK1CAMK     
CHEK2CAMK     
PRKD1CAMK     
CDC2CMGC     
CDC2CMGC     
CDK2CMGC     
CDK5CMGC     
CSNK2A1CMGC     
GSK3ACMGC     
GSK3BCMGC     
MAPK1CMGC     
MAPK10CMGC     
MAPK11CMGC     
MAPK12CMGC     
MAPK13CMGC     
MAPK14CMGC     
MAPK8CMGC     
MAPK9CMGC     
CHUKOther     
ABL1TK     
LCKTK     
SRCTK