Kinase profiling results of kinases in KIF 3FMJA_FMJ (MAPK14, PDB code: 3FMJ, chain A)
Template Kinase: MAPK14
Template inhibitor: Imidazo[1,2-a]pyridine deriv. 1

 6 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
RPS6KB1AGC
CDK2CMGC
MAPK14CMGC
FGFR1TK
FGFR2TK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
RPS6KB1AGC 
CDC2CMGC 
CDC2CMGC 
CDK2CMGC 
MAPK14CMGC 
FGFR1TK 
FGFR2TK