Kinase profiling results of kinases in KIF 3GCSA_BAX (MAPK14, PDB code: 3GCS, chain A)
Template Kinase: MAPK14
Template inhibitor: Sorafenib

 7 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
MAPK9CMGC 
MAPK11CMGC 
MAPK14CMGC 
ABL1TK 
ABL2TK 
LCKTK 
LIMK1TKL 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
MAPK11CMGC 
MAPK14CMGC 
MAPK9CMGC 
ABL1TK 
ABL2TK 
LCKTK 
LIMK1TKL