Kinase profiling results of kinases in KIF 3HL7A_I47 (MAPK14, PDB code: 3HL7, chain A)
Template Kinase: MAPK14
Template inhibitor: DB07943

 4 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
MAPK1CMGC
MAPK10CMGC
MAPK11CMGC
MAPK14CMGC

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
MAPK1CMGC
MAPK10CMGC
MAPK11CMGC
MAPK14CMGC