Kinase profiling results of kinases in KIF 3ITZA_P66 (MAPK14, PDB code: 3ITZ, chain A)
Template Kinase: MAPK14
Template inhibitor: P66

 15 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C
CHEK1CAMK  
STK17ACAMK  
MKNK2CAMK  
CDK2CMGC  
GSK3ACMGC  
MAPK1CMGC  
MAPK10CMGC  
MAPK8CMGC  
MAPK11CMGC  
MAPK12CMGC  
MAPK13CMGC  
MAPK14CMGC  
LCKTK  
PTK6TK  

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C
CHEK1CAMK     
MKNK2CAMK     
STK17ACAMK     
CDC2CMGC     
CDC2CMGC     
CDK2CMGC     
GSK3ACMGC     
MAPK1CMGC     
MAPK10CMGC     
MAPK11CMGC     
MAPK12CMGC     
MAPK13CMGC     
MAPK14CMGC     
MAPK8CMGC     
LCKTK     
PTK6TK