Kinase profiling results of kinases in KIF 3OCGA_OCG (MAPK14, PDB code: 3OCG, chain A)
Template Kinase: MAPK14
Template inhibitor: OCG

8 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C
PDPK1AGC   
GSK3BCMGC   
MAPK10CMGC   
MAPK8CMGC   
MAPK14CMGC   
ABL1TK   
FGFR1TK   
LCKTK   

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C
PDPK1AGC  
GSK3BCMGC  
MAPK10CMGC  
MAPK14CMGC  
MAPK8CMGC  
ABL1TK  
FGFR1TK  
LCKTK