Kinase profiling results of kinases in KIF 2PZYA_B18 (MAPKAPK2, PDB code: 2PZY, chain A)
Template Kinase: MAPKAPK2
Template inhibitor: carboline analog, 76

11 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C C C C
PDPK1AGC      
PRKCDAGC      
PRKCQAGC      
MAPKAPK23      
CDK5CMGC      
GSK3BCMGC      
AURKAOther      
AURKBOther      
AURKCOther      
PLK1Other      

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C
PDPK1AGC     
PRKCAAGC     
PRKCDAGC     
PRKCQAGC     
MAPKAPK2CAMK     
CDK5CMGC     
GSK3BCMGC     
AURKAOther     
AURKBOther     
AURKCOther     
PLK1Other