Kinase profiling results of kinases in KIF 3GOKA_P4O (MAPKAPK2, PDB code: 3GOK, chain A)
Template Kinase: MAPKAPK2
Template inhibitor: 2jbo

 20 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C
CHEK1CAMK  
STK11CAMK  
MAPKAPK23  
PIM1CAMK  
PRKD1CAMK  
CHEK2CAMK  
CDK4CMGC  
CSNK2A1CMGC  
GSK3ACMGC  
GSK3BCMGC  
MAPK8CMGC  
AURKAOther  
CHUKOther  
NEK2Other  
PLK1Other  
MAP3K5STE  

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C
PRKCAAGC  
PRKCZAGC  
CHEK1CAMK  
CHEK2CAMK  
MAPKAPK2CAMK  
MAPKAPK3CAMK  
PIM1CAMK  
PRKD1CAMK  
STK11CAMK  
CDK4CMGC  
CDK6CMGC  
CDK6CMGC  
CSNK2A1CMGC  
GSK3ACMGC  
GSK3BCMGC  
MAPK8CMGC  
AURKAOther  
CHUKOther  
NEK2Other  
PLK1Other  
MAP3K5STE