Kinase profiling results of kinases in KIF 3KC3A_MK2 (MAPKAPK2, PDB code: 3KC3, chain A)
Template Kinase: MAPKAPK2
Template inhibitor: N~4~-[7-(1-Benzofuran-2-Yl)-1h-Indazol-5-Yl]pyrimidine-2,4-Diamine

 4 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
MAPKAPK23
GSK3BCMGC
MAPK8CMGC

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
PRKCAAGC 
MAPKAPK2CAMK 
GSK3BCMGC 
MAPK8CMGC