Kinase profiling results of kinases in KIF 3R2BA_05B (MAPKAPK2, PDB code: 3R2B, chain A)
Template Kinase: MAPKAPK2
Template inhibitor: SB_431542

 4 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
MAPKAPK23
CHEK2CAMK
AURKAOther

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
CHEK2CAMK
MAPKAPK2CAMK
MAPKAPK3CAMK
AURKAOther