Kinase profiling results of kinases in KIF 3FXWA_F10 (MAPKAPK3, PDB code: 3FXW, chain A)
Template Kinase: MAPKAPK3
Template inhibitor: Pyrrolopyridine, 23

6 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C
MAPKAPK23  
CHEK2CAMK  
CDK5CMGC  
NEK2Other  
PLK1Other  

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C C C C
CHEK2CAMK        
MAPKAPK2CAMK        
MAPKAPK3CAMK        
CDK5CMGC        
NEK2Other        
PLK1Other