Kinase profiling results of kinases in KIF 2RFSA_AM8 (MET, PDB code: 2RFS, chain A)
Template Kinase: MET
Template inhibitor: SU11274

 7 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
LTKTK 
JAK2TK 
JAK3TK 
METTK 
RETTK 
NTRK2TK 
NTRK3TK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
JAK2TK 
JAK3TK 
LTKTK 
METTK 
NTRK2TK 
NTRK3TK 
RETTK