Kinase profiling results of kinases in KIF 3RHKA_M97 (MET, PDB code: 3RHK, chain A)
Template Kinase: MET
Template inhibitor: bisindolylmaleimide iv

5 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
CDK2CMGC
PTK2TK
FGFR1TK
METTK
FLT4TK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C
CDK2CMGC     
FGFR1TK     
FLT4TK     
METTK     
PTK2TK