Kinase profiling results of kinases in KIF 3GGFA_GVD (MST4, PDB code: 3GGF, chain A)
Template Kinase: MST4
Template inhibitor: pyrido[4,3-d]pyrimidine deriv. 4n

 4 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
MST4STE
JAK2TK
JAK3TK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
MAP3K8STE
MST4STE
JAK2TK
JAK3TK