Kinase profiling results of kinases in KIF 2VWIA_ANP (OXSR1, PDB code: 2VWI, chain A)
Template Kinase: OXSR1
Template inhibitor: Phosphoaminophosphonic Acid-Adenylate Ester

 17 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
PDPK1AGC
PRKCIAGC
CHEK2CAMK
CDK2CMGC
AURKAOther
NEK2Other
NEK7Other
OXSR1STE
MAP2K4STE
ABL1TK
EGFRTK
IGF1RTK
RETTK
SRCTK
HCKTK
ZAP70TK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
GRK6AGC
PDPK1AGC
PRKCIAGC
CHEK2CAMK
CDK2CMGC
AURKAOther
NEK2Other
NEK7Other
OXSR1STE
ABL1TK
EGFRTK
HCKTK
IGF1RTK
RETTK
SRCTK
ZAP70TK