Kinase profiling results of kinases in KIF 1H1WA_ATP (PDPK1, PDB code: 1H1W, chain A)
Template Kinase: PDPK1
Template inhibitor: Adenosine-5'-triphosphate

 30 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
AKT2AGC
PDPK1AGC
PRKCIAGC
RPS6KA1AGC
RPS6KA1CAMK
STK11CAMK
DAPK1CAMK
MAPKAPK23
PIM1CAMK
CHEK2CAMK
CDK2CMGC
CDK7CMGC
CSNK2A1CMGC
GSK3BCMGC
MAPK10CMGC
MAPK12CMGC
AURKAOther
NEK2Other
EIF2AK2Other
PLK1Other
PLK4Other
TTKOther
OXSR1STE
STK24STE
ABL1TK
EGFRTK
EPHA3TK
FGFR2TK
RETTK
IRAK4TKL

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
AKT2AGC
GRK6AGC
PDPK1AGC
PRKCIAGC
RPS6KA1AGC
CHEK2CAMK
DAPK1CAMK
MAPKAPK2CAMK
PIM1CAMK
STK11CAMK
CDK2CMGC
CDK7CMGC
CSNK2A1CMGC
GSK3BCMGC
MAPK10CMGC
MAPK12CMGC
AURKAOther
NEK2Other
PLK1Other
TTKOther
OXSR1STE
STK24STE
ABL1TK
EGFRTK
EPHA3TK
FGFR2TK
RETTK
IRAK4TKL