Kinase profiling results of kinases in KIF 1Z5MA_LI8 (PDPK1, PDB code: 1Z5M, chain A)
Template Kinase: PDPK1
Template inhibitor: BX-320

11 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C
PDPK1AGC  
STK33CAMK  
CDK2CMGC  
MAPK10CMGC  
MAPK8CMGC  
MAPK9CMGC  
AURKAOther  
AURKBOther  
EGFRTK  
LYNTK  

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C
PDPK1AGC   
STK33CAMK   
CDC2CMGC   
CDC2CMGC   
CDK2CMGC   
MAPK10CMGC   
MAPK8CMGC   
MAPK9CMGC   
AURKAOther   
AURKBOther   
EGFRTK   
LYNTK