Kinase profiling results of kinases in KIF 2PE0A_39Z (PDPK1, PDB code: 2PE0, chain A)
Template Kinase: PDPK1
Template inhibitor: 2pe0

20 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
PDPK1AGC
RPS6KA1AGC
RPS6KA1CAMK
RPS6KA2AGC
RPS6KA2CAMK
BRSK1CAMK
BRSK2CAMK
STK11CAMK
MELKCAMK
NUAK1CAMK
STK33CAMK
STK17ACAMK
PHKG1CAMK
CHEK2CAMK
CDK2CMGC
CDK5CMGC
GSK3ACMGC
GSK3BCMGC
AURKAOther
AURKBOther
RETTK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C
PDPK1AGC  
RPS6KA1AGC  
RPS6KA2AGC  
BRSK1CAMK  
BRSK2CAMK  
CHEK2CAMK  
MELKCAMK  
NUAK1CAMK  
PHKG1CAMK  
STK11CAMK  
STK17ACAMK  
STK33CAMK  
CDK2CMGC  
CDK5CMGC  
CDK6CMGC  
CDK6CMGC  
GSK3ACMGC  
GSK3BCMGC  
AURKAOther  
AURKBOther  
RETTK