Kinase profiling results of kinases in KIF 3NAYA_MP6 (PDPK1, PDB code: 3NAY, chain A)
Template Kinase: PDPK1
Template inhibitor: ZINC13474643

 20 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C
PDPK1AGC  
PRKCDAGC  
PRKCQAGC  
CHEK1CAMK  
CDK2CMGC  
CDK4CMGC  
CSNK2A1CMGC  
DYRK1ACMGC  
DYRK1BCMGC  
GSK3BCMGC  
MAPK1CMGC  
MAPK10CMGC  
MAPK8CMGC  
MAPK14CMGC  
AURKAOther  
PLK1Other  
PLK2Other  
PLK3Other  
JAK2TK  
JAK3TK  

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
PDPK1AGC
PRKCDAGC
PRKCQAGC
CHEK1CAMK
CDK2CMGC
CDK4CMGC
CSNK2A1CMGC
DYRK1ACMGC
DYRK1BCMGC
GSK3BCMGC
MAPK1CMGC
MAPK10CMGC
MAPK14CMGC
MAPK8CMGC
AURKAOther
PLK1Other
PLK2Other
PLK3Other
JAK2TK
JAK3TK