Kinase profiling results of kinases in KIF 3QCQA_3Q0 (PDPK1, PDB code: 3QCQ, chain A)
Template Kinase: PDPK1
Template inhibitor: Kinome_1060

20 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
PDPK1AGC 
PRKCDAGC 
CHEK1CAMK 
PIM1CAMK 
PRKD1CAMK 
CDK2CMGC 
CDK4CMGC 
CSNK2A1CMGC 
GSK3BCMGC 
MAPK1CMGC 
MAPK8CMGC 
MAPK14CMGC 
AURKBOther 
ABL1TK 
CSKTK 
JAK2TK 
JAK3TK 
RETTK 
IRAK4TKL 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C
PDPK1AGC  
PRKCDAGC  
CHEK1CAMK  
PIM1CAMK  
PRKD1CAMK  
CDC2CMGC  
CDC2CMGC  
CDK2CMGC  
CDK4CMGC  
CSNK2A1CMGC  
GSK3BCMGC  
MAPK1CMGC  
MAPK14CMGC  
MAPK8CMGC  
AURKBOther  
ABL1TK  
CSKTK  
JAK2TK  
JAK3TK  
RETTK  
IRAK4TKL