Kinase profiling results of kinases in KIF 3QCYA_3Q3 (PDPK1, PDB code: 3QCY, chain A)
Template Kinase: PDPK1
Template inhibitor: (3s,6r)-1-[2-Amino-6-(3-Amino-2h-Indazol-6-Yl)pyrimidin-4-Yl]-6-Methyl-N-Phenylpiperidine-3-Carboxamide

5 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
PDPK1AGC
CDK2CMGC
AURKAOther
AURKBOther
JAK2TK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
PDPK1AGC
CDK2CMGC
AURKAOther
AURKBOther
JAK2TK