Kinase profiling results of kinases in KIF 3JPVA_1DR (PIM1, PDB code: 3JPV, chain A)
Template Kinase: PIM1
Template inhibitor: 1DR

 5 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
PIM1CAMK
PIM2CAMK
PIM3CAMK
AURKAOther
AURKBOther

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C
PIM1CAMK   
PIM2CAMK   
PIM3CAMK   
AURKAOther   
AURKBOther