Kinase profiling results of kinases in KIF 3AQVA_TAK (PRKAA2, PDB code: 3AQV, chain A)
Template Kinase: PRKAA2
Template inhibitor: dorsomorphin

12 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C
PRKAA2CAMK   
MELKCAMK   
AURKAOther   
ULK1Other   
ABL1TK   
ABL2TK   
EPHA1TK   
FGFR1TK   
SRCTK   
YES1TK   
NTRK2TK   
NTRK3TK   

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C
MELKCAMK    
AURKAOther    
ULK1Other    
ABL1TK    
ABL2TK    
EPHA1TK    
FGFR1TK    
NTRK2TK    
NTRK3TK    
SRCTK    
YES1TK